c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells <sup>†</sup>

c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells <sup>†</sup>

Angiogenic vasa vasorum (VV) expansion plays an essential role in the pathogenesis of hypoxia-induced pulmonary hypertension (PH), a cardiovascular disease. We previously showed that extracellular ATP released under hypoxic conditions is an autocrine/paracrine, the angiogenic factor for pulmonary ar...

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Bibliographic Details
Main Authors: Derek Strassheim, Vijaya Karoor, Hala Nijmeh, Philip Weston, Martin Lapel, Jerome Schaack, Timothy Sullivan, Edward C. Dempsey, Kurt R. Stenmark, Evgenia Gerasimovskaya
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
vasa vasorum
angiogenesis
endothelial cells
extracellular atp
akt
mtor transcription factors
c-jun
foxo3a
c-myc
Online Access:https://www.mdpi.com/2073-4409/9/2/416

Internet

https://www.mdpi.com/2073-4409/9/2/416

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