satuRn: Scalable analysis of differential transcript usage for bulk and single-cell RNA-sequencing applications [version 2; peer review: 2 approved]

Alternative splicing produces multiple functional transcripts from a single gene. Dysregulation of splicing is known to be associated with disease and as a hallmark of cancer. Existing tools for differential transcript usage (DTU) analysis either lack in performance, cannot account for complex exper...

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Bibliographic Details
Main Authors: Koen Van den Berge, Kristoffer Vitting-Seerup, Jeroen Gilis, Lieven Clement
Format: Article
Language:English
Published: F1000 Research Ltd 2022-08-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/10-374/v2