2045 The role of TGFβ in driving early cystic fibrosis lung disease

OBJECTIVES/SPECIFIC AIMS: Transforming growth factor-beta (TGFβ) is a genetic modifier of cystic fibrosis (CF) lung disease. TGFβ’s pulmonary levels in young CF patients and its mechanism of action in CF are unknown. We examined TGFβ levels in children with CF and investigated responses of human air...

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Bibliographic Details
Main Authors: Elizabeth L. Kramer, William Hardie, Kristin Hudock, Cynthia Davidson, Alicia Ostmann, John P. Clancy
Format: Article
Language:English
Published: Cambridge University Press 2018-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866118001395/type/journal_article