A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria

A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria

The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bacteria, the uptake of anti-infectives is especially...

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Bibliographic Details
Main Authors: Robert Richter, Mohamed.A.M. Kamal, Mariel A. García-Rivera, Jerome Kaspar, Maximilian Junk, Walid A.M. Elgaher, Sanjay Kumar Srikakulam, Alexander Gress, Anja Beckmann, Alexander Grißmer, Carola Meier, Michael Vielhaber, Olga Kalinina, Anna K.H. Hirsch, Rolf W. Hartmann, Mark Brönstrup, Nicole Schneider-Daum, Claus-Michael Lehr
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Materials Today Bio
Subjects:
Antibiotic screening
Machine learning
3D-printing
Starch hydrogel
Structure–permeability relationships
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006420300442

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http://www.sciencedirect.com/science/article/pii/S2590006420300442

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