Nucleus Pulposus Cells Induce M2 Polarization of RAW264.7 via CX3CL1/CX3CR1 Pathway and M2 Macrophages Promote Proliferation and Anabolism of Nucleus Pulposus Cells

Background. The mechanisms underlying M2 macrophage polarization induced by nucleus pulposus (NP) cells are unclear. The effects that M2-polarized macrophages have on NP cells are also controversial. Methods. Transcriptome sequencing was performed to detect the gene change profiles between NP cells...

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Bibliographic Details
Main Authors: Xiao-Tao Wu, Bo-Wen Wan, Xin-Min Feng, Yu-Ping Tao, Yong-Xiang Wang, Hui-Hui Sun
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2023/6400162