Imputation-Based Whole-Genome Sequence Association Study Reveals Constant and Novel Loci for Hematological Traits in a Large-Scale Swine F2 Resource Population

Imputation-Based Whole-Genome Sequence Association Study Reveals Constant and Novel Loci for Hematological Traits in a Large-Scale Swine F2 Resource Population

The whole-genome sequences of progenies with low-density single-nucleotide polymorphism (SNP) genotypes can be imputed with high accuracy based on the deep-coverage sequences of key ancestors. With this imputation technology, a more powerful genome-wide association study (GWAS) can be carried out us...

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Bibliographic Details
Main Authors: Guorong Yan, Tianfu Guo, Shijun Xiao, Feng Zhang, Wenshui Xin, Tao Huang, Wenwu Xu, Yiping Li, Zhiyan Zhang, Lusheng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
GWAS
imputation
hematology
pig
whole-genome sequence
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00401/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00401/full

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