Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection

Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection

Abstract Background Tick-borne encephalitis virus (TBEV) is a member of the Flaviviridae family, Flavivirus genus, which includes several important human pathogens. It is responsible for neurological symptoms that may cause permanent disability or death, and, from a medical point of view, is the maj...

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Bibliographic Details
Main Authors: Mazigh Fares, Marielle Cochet-Bernoin, Gaëlle Gonzalez, Claudia N. Montero-Menei, Odile Blanchet, Alexandra Benchoua, Claire Boissart, Sylvie Lecollinet, Jennifer Richardson, Nadia Haddad, Muriel Coulpier
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Neuroinflammation
Subjects:
Neurotropic virus
Flavivirus
Tick-borne encephalitis virus
Central nervous system
Human neuronal/glial cells
Viral tropism
Online Access:http://link.springer.com/article/10.1186/s12974-020-01756-x

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http://link.springer.com/article/10.1186/s12974-020-01756-x

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