Modulation of Estrogen Receptor Alpha (ERα) and Tumor Suppressor Gene BRCA1 in Breast Cancer Cells by Bazedoxifene Acetate (BZA)

Modulation of Estrogen Receptor Alpha (ERα) and Tumor Suppressor Gene BRCA1 in Breast Cancer Cells by Bazedoxifene Acetate (BZA)

Selective estrogen receptor modulators (SERMs) are steroid analogs with dual functionality, acting as partial estrogen receptor agonists to preserve postmenopausal bone density and as estrogen receptor antagonists in breast tissue. Bazedoxifene acetate (BZA) is an FDA-approved, third-generation SERM...

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Bibliographic Details
Main Authors: Monica Szmyd, Aisha Zanib, Victoria Behlow, Erin Hallman, Samantha Pfiffner, Raquel Yaldo, Nina Prudhomme, Katelyn Farrar, Sumi Dinda
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
ERα
BRCA1
estrogen receptor
tumor suppressor gene
bazedoxifene acetate
breast cancer
Online Access:https://www.mdpi.com/2072-6694/16/4/699

Internet

https://www.mdpi.com/2072-6694/16/4/699

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