Systematic evaluation of oligodeoxynucleotide binding and hybridization to modified multi-walled carbon nanotubes

Systematic evaluation of oligodeoxynucleotide binding and hybridization to modified multi-walled carbon nanotubes

Abstract Background In addition to conventional chemotherapeutics, nucleic acid-based therapeutics like antisense oligodeoxynucleotides (AS-ODN) represent a novel approach for the treatment of bladder cancer (BCa). An efficient delivery of AS-ODN to the urothelium and then into cancer cells might be...

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Bibliographic Details
Main Authors: Anika Kaufmann, Silke Hampel, Christiane Rieger, David Kunhardt, Darja Schendel, Susanne Füssel, Bernd Schwenzer, Kati Erdmann
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Nanobiotechnology
Subjects:
Antisense oligodeoxynucleotides
Biocompatibility
Bladder cancer
Carbon nanotubes
Carrier strand
Functionalization
Online Access:http://link.springer.com/article/10.1186/s12951-017-0288-z

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http://link.springer.com/article/10.1186/s12951-017-0288-z

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