Live Biosensors for Ultrahigh-Throughput Screening of Antimicrobial Activity against Gram-Negative Bacteria

Live Biosensors for Ultrahigh-Throughput Screening of Antimicrobial Activity against Gram-Negative Bacteria

Gram-negative pathogens represent an urgent threat due to their intrinsic and acquired antibiotic resistance. Many recent drug candidates display prominent antimicrobial activity against Gram-positive bacteria being inefficient against Gram-negative pathogens. Ultrahigh-throughput, microfluidics-bas...

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Bibliographic Details
Main Authors: Margarita N. Baranova, Polina A. Babikova, Arsen M. Kudzhaev, Yuliana A. Mokrushina, Olga A. Belozerova, Maxim A. Yunin, Sergey Kovalchuk, Alexander G. Gabibov, Ivan V. Smirnov, Stanislav S. Terekhov
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
ultrahigh-throughput screening
live biosensors
antibiotic discovery
gram-negative pathogens
microfluidic droplet cocultivation
efficient promoters
Online Access:https://www.mdpi.com/2079-6382/10/10/1161

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https://www.mdpi.com/2079-6382/10/10/1161

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