THE HYPOXIA INDUCIBLE FACTOR (HIF) PATHWAY IN AML: THERAPEUTIC TARGETING
The increase in levels of the hormone erythropoietin, which leads to increased production of red blood cells in response to hypoxia, was a physiological response known in the early 20th century. However, the mechanism of the cellular reaction to hypoxia was unknown. William G. Kaelin Jr., Peter J. R...
| Autor principal: | |
|---|---|
| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Elsevier
2024-12-01
|
| Colecção: | Hematology, Transfusion and Cell Therapy |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2531137924029390 |