Rapid evaluation of heterologous chimeric RBD-dimer mRNA vaccine for currently-epidemic Omicron sub-variants as booster shot after inactivated vaccine

Rapid evaluation of heterologous chimeric RBD-dimer mRNA vaccine for currently-epidemic Omicron sub-variants as booster shot after inactivated vaccine

With continuous mutations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the severe immune escape of Omicron sub-variants urges the development of next-generation broad-spectrum vaccines, especially as booster jabs after high-level vaccination coverage of inactivated vaccines in Ch...

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Bibliographic Details
Main Authors: Qian Chen, Pei Du, Yuxuan Han, Xuehui Ma, Rong Zhang, Xiaoyu Rong, Xu Zhao, Renyi Ma, Huiting Yang, Anqi Zheng, Qingrui Huang, Jinghua Yan, Hui Wang, Xin Zhao, Lianpan Dai, George F. Gao, Qihui Wang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Biosafety and Health
Subjects:
SARS-CoV-2
RBD-dimer
mRNA Vaccine
Broad-spectrum
Omicron
BA.5
Online Access:http://www.sciencedirect.com/science/article/pii/S2590053623000228

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http://www.sciencedirect.com/science/article/pii/S2590053623000228

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