Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data

Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data

Abstract Ophthalmic epidemiology is concerned with the prevalence, distribution and other factors relating to human eye disease. While observational studies cannot avoid confounding factors from interventions, human eye composition and structure are unique, thus, eye disease pathogenesis, which grea...

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Bibliographic Details
Main Authors: Jiaxin Li, Cong Li, Yu Huang, Peng Guan, Desheng Huang, Honghua Yu, Xiaohong Yang, Lei Liu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Translational Medicine
Subjects:
Causality
Eye disease
Instrumental variables
Mendelian randomization
Online Access:https://doi.org/10.1186/s12967-022-03822-9

Internet

https://doi.org/10.1186/s12967-022-03822-9

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