P-selectin expression tracks cerebral atrophy in Mexican-Americans

P-selectin expression tracks cerebral atrophy in Mexican-Americans

Background and Purpose. We hypothesized that the P-selectin (SELP) gene, localized to a region on chromosome 1q24, pleiotropically contributes to increased blood pressure (BP) and cerebral atrophy. We tested this hypothesis by performing genetic correlation analyses for thirteen mRNA gene-expressio...

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Bibliographic Details
Main Authors: Peter eKochunov, David eGlahn, Elliott eHong, Jack L Lancaster, Joanne eCurran, Matthew eJohnson, Anderson eWinkler, Henry eHolcomb, Jack eKent, Braxton eMitchell, Valeria eKochunov, Rene eOlvera, Shelley eCole, Thomas eDyer, Eric eMoses, Harald eGoring, Laura eAlmasy, Ravi eDuggirala, John eBlangero
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Genetics
Subjects:
Aging
Gene Expression
Genetics
Hypertension
P-Selectin
DTI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00065/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00065/full

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