MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway

MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway

Abstract Glioma-associated macrophages (GAMs) are pivotal chains in the tumor immune microenvironment (TIME). GAMs mostly display M2-like phenotypes with anti-inflammatory features related to the malignancy and progression of cancers. Extracellular vesicles derived from immunosuppressive GAMs (M2-EV...

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Bibliographic Details
Main Authors: Chao Xu, Pan Wang, Haiyan Guo, Chuan Shao, Bin Liao, Sheng Gong, Yanghao Zhou, Bingjie Yang, Haotian Jiang, Gang Zhang, Nan Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01492-0

Internet

https://doi.org/10.1038/s41420-023-01492-0

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