CircSMARCA5 Regulates VEGFA mRNA Splicing and Angiogenesis in Glioblastoma Multiforme Through the Binding of SRSF1

CircSMARCA5 Regulates VEGFA mRNA Splicing and Angiogenesis in Glioblastoma Multiforme Through the Binding of SRSF1

Circular RNAs are a large group of RNAs whose cellular functions are still being investigated. We recently proposed that circSMARCA5 acts as sponge for the splicing factor Serine and Arginine Rich Splicing Factor 1 (SRSF1) in glioblastoma multiforme (GBM). After demonstrating by RNA immunoprecipitat...

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Bibliographic Details
Main Authors: Davide Barbagallo, Angela Caponnetto, Duilia Brex, Federica Mirabella, Cristina Barbagallo, Giovanni Lauretta, Antonio Morrone, Francesco Certo, Giuseppe Broggi, Rosario Caltabiano, Giuseppe M. Barbagallo, Vittoria Spina-Purrello, Marco Ragusa, Cinzia Di Pietro, Thomas B. Hansen, Michele Purrello
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
circular RNA
hsa_circ_0001445
RNA binding proteins
alternative splicing
glioblastoma multiforme
angiogenesis
VEGFA
Online Access:https://www.mdpi.com/2072-6694/11/2/194

Internet

https://www.mdpi.com/2072-6694/11/2/194

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