HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis

HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis

Abstract Background The role of hypoxia-inducible factor-1α (HIF-1α) in primary colorectal cancer (CRC) and colorectal liver metastasis (CRLM) has remained unclear. The aim of this study was to investigate HIF-1α expression and its association with prognosis in patients with CRLM with a focus on hep...

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Bibliographic Details
Main Authors: Yuma Wada, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Yu Saito, Chie Takasu, Shinichiro Yamada, Mitsuo Shimada
Format: Article
Language:English
Published: BMC 2020-09-01
Series:World Journal of Surgical Oncology
Subjects:
Colorectal liver metastasis
HIF-1α
Prognostic factor
Molecular biology
Online Access:http://link.springer.com/article/10.1186/s12957-020-02012-5

Internet

http://link.springer.com/article/10.1186/s12957-020-02012-5

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