Multicellular architecture of malignant breast epithelia influences mechanics.
Cell-matrix and cell-cell mechanosensing are important in many cellular processes, particularly for epithelial cells. A crucial question, which remains unexplored, is how the mechanical microenvironment is altered as a result of changes to multicellular tissue structure during cancer progression. In...
Main Authors: | Gautham Venugopalan, David B Camarillo, Kevin D Webster, Clay D Reber, James A Sethian, Valerie M Weaver, Daniel A Fletcher, Hana El-Samad, Chris H Rycroft |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4128597?pdf=render |
Similar Items
-
Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling
by: Benjamin L Ricca, et al.
Published: (2018-03-01) -
Mechanisms and mechanics of cell competition in epithelia
by: Vincent, J, et al.
Published: (2013) -
Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture
by: Knouse, Kristin Ann, et al.
Published: (2020) -
Integrins Cooperate With the EGFR/Ras Pathway to Preserve Epithelia Survival and Architecture in Development and Oncogenesis
by: Andrea Valencia-Expósito, et al.
Published: (2022-06-01) -
In Vitro Effects of Permethrin on Sinonasal Epithelia
by: Jivianne T. Lee MD, et al.
Published: (2022-07-01)