High platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs

High platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs

Abstract Background Rating lymphocytes (TILs) are a prognostic marker in breast cancer and high TIL infiltration correlates with better patient outcomes. Meanwhile, parameters involving immune cells in peripheral blood have also been established as prognostic markers. High platelet-to-lymphocyte rat...

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Bibliographic Details
Main Authors: Hiroko Onagi, Yoshiya Horimoto, Asumi Sakaguchi, Daiki Ikarashi, Naotake Yanagisawa, Takayuki Nakayama, Tetsuya Nakatsura, Yumiko Ishizuka, Ritsuko Sasaki, Junichiro Watanabe, Mitsue Saito, Harumi Saeki, Takuo Hayashi, Atsushi Arakawa, Takashi Yao, Shigehisa Kitano
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Breast Cancer Research
Subjects:
Triple-negative breast cancer
Tumor-infiltrating lymphocyte
Regulatory T-cells
Platelet-to-lymphocyte ratio
Multiplexed fluorescent immunohistochemistry
Online Access:https://doi.org/10.1186/s13058-022-01563-7

Internet

https://doi.org/10.1186/s13058-022-01563-7

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