The poly(C)-binding protein Pcbp2 is essential for CD4+ T cell activation and proliferation

The poly(C)-binding protein Pcbp2 is essential for CD4+ T cell activation and proliferation

Summary: The RNA-binding protein Pcbp2 is widely expressed in the innate and adaptive immune systems and is essential for mouse development. To determine whether Pcbp2 is required for CD4+ T cell development and function, we derived mice with conditional Pcbp2 deletion in CD4+ T cells and assessed t...

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Bibliographic Details
Main Authors: Massimo Martinelli, Gabrielle Aguilar, David S.M. Lee, Andrew Kromer, Nhu Nguyen, Benjamin J. Wilkins, Tatiana Akimova, Ulf H. Beier, Louis R. Ghanem
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Molecular biology
Immunology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222021332

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http://www.sciencedirect.com/science/article/pii/S2589004222021332

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