TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination

Abstract Tumor necrosis factor receptor-associated factor 6 (TRAF6) is an E3 ubiquitin ligase that is extensively involved in the autophagy process by interacting with diverse autophagy initiation and autophagosome maturation molecules. However, whether TRAF6 interacts with lysosomal proteins to reg...

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Bibliographic Details
Main Authors: Qinmei Ma, Jialin Yu, Li Liu, Xiaoyan Ma, Jiaxue Zhang, Jiamei Zhang, Xiaoping Wang, Guangcun Deng, Xiaoling Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01731-4