The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex.

The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex.

M. africanum West African 2 constitutes an ancient lineage of the M. tuberculosis complex that commonly causes human tuberculosis in West Africa and has an attenuated phenotype relative to M. tuberculosis.In search of candidate genes underlying these differences, the genome of M. africanum West Afri...

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Bibliographic Details
Main Authors: Stephen D Bentley, Iñaki Comas, Josephine M Bryant, Danielle Walker, Noel H Smith, Simon R Harris, Scott Thurston, Sebastien Gagneux, Jonathan Wood, Martin Antonio, Michael A Quail, Florian Gehre, Richard A Adegbola, Julian Parkhill, Bouke C de Jong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3289620?pdf=render

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http://europepmc.org/articles/PMC3289620?pdf=render

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