Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopia

Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopia

Abstract Background Population studies suggest that genetic factors play an important role in refractive error development; however, the precise role of genetic background and the composition of the signaling pathways underlying refractive eye development remain poorly understood. Methods Here, we a...

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Bibliographic Details
Main Authors: Tatiana V. Tkatchenko, Rupal L. Shah, Takayuki Nagasaki, Andrei V. Tkatchenko
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Medical Genomics
Subjects:
Myopia
Refractive eye development
Genetic networks
Signaling pathways
Genetic variation
RNA-seq
Online Access:http://link.springer.com/article/10.1186/s12920-019-0560-1

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http://link.springer.com/article/10.1186/s12920-019-0560-1

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