Cerebral blood flow in presymptomatic MAPT and GRN mutation carriers: A longitudinal arterial spin labeling study

Cerebral blood flow in presymptomatic MAPT and GRN mutation carriers: A longitudinal arterial spin labeling study

Objective: Frontotemporal dementia (FTD) is characterized by behavioral disturbances and language problems. Familial forms can be caused by genetic defects in microtubule-associated protein tau (MAPT), progranulin (GRN), and C9orf72. In light of upcoming clinical trials with potential disease-modify...

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Bibliographic Details
Main Authors: Elise G.P. Dopper, PhD, Vicky Chalos, Eidrees Ghariq, Tom den Heijer, MD PhD, Anne Hafkemeijer, MSc, Lize C. Jiskoot, MSc, Inge de Koning, PhD, Harro Seelaar, MD PhD, Rick van Minkelen, PhD, Matthias J.P. van Osch, PhD, Serge A.R.B. Rombouts, PhD, John C. van Swieten, MD PhD
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:NeuroImage: Clinical
Subjects:
Frontotemporal dementia
Arterial spin labeling
Cerebral blood flow
Presymptomatic
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158216301371

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http://www.sciencedirect.com/science/article/pii/S2213158216301371

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