Hidden Markov Model-Based CNV Detection Algorithms for Illumina Genotyping Microarrays
Somatic alterations in DNA copy number have been well studied in numerous malignancies, yet the role of germline DNA copy number variation in cancer is still emerging. Genotyping microarrays generate allele-specific signal intensities to determine genotype, but may also be used to infer DNA copy num...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-01-01
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| Series: | Cancer Informatics |
| Online Access: | https://doi.org/10.4137/CIN.S16345 |