Preventive Effects of Thinned Apple Extracts on TNF-α-Induced Intestinal Tight Junction Dysfunction in Caco-2 Cells through Myosin Light Chain Kinase Suppression

Preventive Effects of Thinned Apple Extracts on TNF-α-Induced Intestinal Tight Junction Dysfunction in Caco-2 Cells through Myosin Light Chain Kinase Suppression

Inflammatory bowel disease (IBD) is associated with intestinal epithelial barrier dysfunction and elevation of proinflammatory cytokines such as TNF-α. Tight junctions (TJ) control the paracellular barrier of the gut. Thinned apples are an indispensable horticultural agro-waste for apple cultivation...

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Bibliographic Details
Main Authors: Joo-Yeon Lee, Choon Young Kim
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Foods
Subjects:
thinned apple
tight junction
myosin light chain kinase
intestinal epithelial barrier
inflammatory bowel disease
Online Access:https://www.mdpi.com/2304-8158/11/12/1714

Internet

https://www.mdpi.com/2304-8158/11/12/1714

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