Non-cell-autonomous regulation of mTORC2 by Hedgehog signaling maintains lipid homeostasis

Summary: Organisms allocate energetic resources between essential cellular processes to maintain homeostasis and, in turn, maximize fitness. The nutritional regulators of energy homeostasis have been studied in detail; however, how developmental signals might impinge on these pathways to govern meta...

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Bibliographic Details
Main Authors: Kylie R. VanDerMolen, Martin A. Newman, Peter C. Breen, Yunjing Gao, Laura A. Huff, Robert H. Dowen
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724015420