Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavir

<p>Abstract</p> <p>Background</p> <p>Aspartyl protease inhibitors (PIs) used to treat HIV belong to an important group of drugs that influence significantly endothelial cell functioning and angiogenic capacity, although specific mechanisms are poorly understood. Recentl...

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Bibliographic Details
Main Authors: Chao Ying, Hurford Rosemary, Grigorian Aline, Patrick Christina, Langford T Dianne
Format: Article
Language:English
Published: BMC 2008-02-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/9/27