MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

ABSTRACT African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these proteins is unknown. This study iden...

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Bibliographic Details
Main Authors: Keshan Zhang, Bo Yang, Chaochao Shen, Ting Zhang, Yu Hao, Dajun Zhang, Huanan Liu, Xijuan Shi, Guoli Li, Jinke Yang, Dan Li, Zixiang Zhu, Hong Tian, Fan Yang, Yi Ru, Wei Jun Cao, Jianhong Guo, Jijun He, Haixue Zheng, Xiangtao Liu
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
ASFV
MGF360-9L
JAK/STAT signal pathway
STAT1/2
virulence factor
immune escape
Online Access:https://journals.asm.org/doi/10.1128/mbio.02330-21

Internet

https://journals.asm.org/doi/10.1128/mbio.02330-21

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