Thrombotic microangiopathy mediates poor prognosis among lupus nephritis via complement lectin and alternative pathway activation

Thrombotic microangiopathy mediates poor prognosis among lupus nephritis via complement lectin and alternative pathway activation

ObjectiveThe pathogenesis of thrombotic microangiopathy (TMA) in lupus nephritis (LN) remains complicated. This study aimed to detect the deposition of complement lectin pathway (LP) and alternative pathway (AP) components in renal tissues, then evaluate the clinicopathological characteristics and r...

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Bibliographic Details
Main Authors: Binshan Zhang, Guolan Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
lupus nephritis
thrombotic microangiopathy
lectin pathway
alternative pathway
complement
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1081942/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1081942/full

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