Inflammasome modulation with P2X7 inhibitor A438079-loaded dressings for diabetic wound healing

Inflammasome modulation with P2X7 inhibitor A438079-loaded dressings for diabetic wound healing

The inflammasome is a multiprotein complex critical for the innate immune response to injury. Inflammasome activation initiates healthy wound healing, but comorbidities with poor healing, including diabetes, exhibit pathologic, sustained activation with delayed resolution that prevents healing progr...

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Bibliographic Details
Main Authors: Jordan R. Yaron, Selin Bakkaloglu, Nicole A. Grigaitis, Farhan H. Babur, Sophia Macko, Samantha Rhodes, Solenne Norvor-Davis, Kaushal Rege
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
wound dressing
silk fibroin
inflammasome
small molecule
drug delivery
wound healing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1340405/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1340405/full

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