Deep learning approaches for conformational flexibility and switching properties in protein design

Following the hugely successful application of deep learning methods to protein structure prediction, an increasing number of design methods seek to leverage generative models to design proteins with improved functionality over native proteins or novel structure and function. The inherent flexibilit...

Full description

Bibliographic Details
Main Authors: Lucas S. P. Rudden, Mahdi Hijazi, Patrick Barth
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.928534/full