PD-L1 Expression on Circulating Tumour-Derived Microvesicles as a Complementary Tool for Stratification of High-Grade Serous Ovarian Cancer Patients

PD-L1 Expression on Circulating Tumour-Derived Microvesicles as a Complementary Tool for Stratification of High-Grade Serous Ovarian Cancer Patients

Background: Ovarian cancer (OC) has recently attracted attention for the use of PD-1/PD-L1 axis blocking agents, with durable activity reported only in a subset of patients. The most used biomarker for sensitivity to the PD-1/PD-L1 axis blockade is tumour PD-L1 status by immunohistochemistry. Howeve...

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Bibliographic Details
Main Authors: Alessandra Battaglia, Alessia Piermattei, Alexia Buzzonetti, Tina Pasciuto, Nicole Zampetti, Marco Fossati, Giuseppe Angelico, Valentina Iacobelli, Camilla Nero, Veronica Iannucci, Giovanni Scambia, Anna Fagotti, Andrea Fattorossi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
translational research
microvesicles
biomarkers
PD-L1
immunohistochemistry
ovarian cancer
Online Access:https://www.mdpi.com/2072-6694/13/20/5200

Internet

https://www.mdpi.com/2072-6694/13/20/5200

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