Recent Advances in the Gastrointestinal Complex in Vitro Model for ADME Studies

Recent Advances in the Gastrointestinal Complex in Vitro Model for ADME Studies

Intestinal absorption is a complex process involving the permeability of the epithelial barrier, efflux transporter activity, and intestinal metabolism. Identifying the key factors that govern intestinal absorption for each investigational drug is crucial. To assess and predict intestinal absorption...

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Bibliographic Details
Main Authors: Kazuyoshi Michiba, Kengo Watanabe, Tomoki Imaoka, Daisuke Nakai
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
gastrointestinal absorption
complex in vitro model
microphysiological system
Ussing chamber
organoid
induced pluripotent stem cell
Online Access:https://www.mdpi.com/1999-4923/16/1/37

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https://www.mdpi.com/1999-4923/16/1/37

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