Highly Specialized Carbohydrate Metabolism Capability in Bifidobacterium Strains Associated with Intestinal Barrier Maturation in Early Preterm Infants

Highly Specialized Carbohydrate Metabolism Capability in Bifidobacterium Strains Associated with Intestinal Barrier Maturation in Early Preterm Infants

ABSTRACT “Leaky gut,” or high intestinal barrier permeability, is common in preterm newborns. The role of the microbiota in this process remains largely uncharacterized. We employed both short- and long-read sequencing of the 16S rRNA gene and metagenomes to characterize the intestinal microbiome of...

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Bibliographic Details
Main Authors: Bing Ma, Sripriya Sundararajan, Gita Nadimpalli, Michael France, Elias McComb, Lindsay Rutt, Jose M. Lemme-Dumit, Elise Janofsky, Lisa S. Roskes, Pawel Gajer, Li Fu, Hongqiu Yang, Mike Humphrys, Luke J. Tallon, Lisa Sadzewicz, Marcela F. Pasetti, Jacques Ravel, Rose M. Viscardi
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mBio
Subjects:
preterm infant
gut microbiome
leaky gut
intestinal barrier maturation
human milk oligosaccharides
Bifidobacterium
Online Access:https://journals.asm.org/doi/10.1128/mbio.01299-22

Internet

https://journals.asm.org/doi/10.1128/mbio.01299-22

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