Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia

Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia

Abstract Cerebral blood flow (CBF) measured with arterial spin labelling (ASL) magnetic resonance imaging (MRI) reflects cerebral perfusion, related to metabolism, and arterial transit time (ATT), related to vascular health. Our aim was to investigate the spatial coefficient of variation (sCoV) of C...

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Bibliographic Details
Main Authors: Catherine A. Morgan, Tracy R. Melzer, Reece P. Roberts, Kristina Wiebels, Henk J. M. M. Mutsaerts, Meg J. Spriggs, John C. Dalrymple-Alford, Tim J. Anderson, Nicholas J. Cutfield, Gerard Deib, Josef Pfeuffer, Donna Rose Addis, Ian J. Kirk, Lynette J. Tippett
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02313-z

Internet

https://doi.org/10.1038/s41598-021-02313-z

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