AR Variant ARv567es Induces Carcinogenesis in a Novel Transgenic Mouse Model of Prostate Cancer

AR Variant ARv567es Induces Carcinogenesis in a Novel Transgenic Mouse Model of Prostate Cancer

Androgen deprivation therapy remains the primary treatment modality for patients with metastatic prostate cancer but is uniformly marked by progression to castration-resistant prostate cancer (CRPC) after a period of regression. Continued activation of androgen receptor (AR) signaling is attributed...

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Bibliographic Details
Main Authors: Gang Liu, Cynthia Sprenger, Shihua Sun, Kathryn Soriano Epilepsia, Kathleen Haugk, Xiaotun Zhang, Ilsa Coleman, Peter S. Nelson, Stephen Plymate
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800127

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http://www.sciencedirect.com/science/article/pii/S1476558613800127

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