Inhalation of ACE2-expressing lung exosomes provides prophylactic protection against SARS-CoV-2

Inhalation of ACE2-expressing lung exosomes provides prophylactic protection against SARS-CoV-2

Abstract Continued emergence of SARS-CoV-2 variants of concern that are capable of escaping vaccine-induced immunity highlights the urgency of developing new COVID-19 therapeutics. An essential mechanism for SARS-CoV-2 infection begins with the viral spike protein binding to the human ACE2. Conseque...

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Bibliographic Details
Main Authors: Zhenzhen Wang, Shiqi Hu, Kristen D. Popowski, Shuo Liu, Dashuai Zhu, Xuan Mei, Junlang Li, Yilan Hu, Phuong-Uyen C. Dinh, Xiaojie Wang, Ke Cheng
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45628-x

Internet

https://doi.org/10.1038/s41467-024-45628-x

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