Wee1 epigenetically modulates H2B mono‐ubiquitination at K120 lysine and DNA double‐strand break repair through phosphorylation of H2BY37‐dependent manner in small‐cell lung cancer

Abstract Background DNA damage repair is a crucial mechanism highly related to therapy resistance for various therapeutic strategies. Our previous results have shown that the degree of drug resistance in small‐cell lung cancer (SCLC) cell lines was proportional to both the transcription and expressi...

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Bibliographic Details
Main Authors: Xiaoliang Zhao, Xiaohua Wen, Bin Liu
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Thoracic Cancer
Subjects:
Online Access:https://doi.org/10.1111/1759-7714.14862