Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics
Here, the authors investigate the maturation of Okazaki fragments with human proteins and reveal that initiator RNA removal occurs non-processively and slowly suggesting that additional pathways might exist to accelerate RNA removal in cells.
Main Authors: | Vlad-Stefan Raducanu, Muhammad Tehseen, Amani Al-Amodi, Luay I. Joudeh, Alfredo De Biasio, Samir M. Hamdan |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-34751-2 |
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