Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity

Summary Objective Obesity is associated with delayed insulin absorption upon subcutaneous (s.c.) dosing in humans. The aim of this study was to investigate whether alterations in depot structure and kinetics of the s.c. injection depot contribute to this delay. Methods Rats fed a high‐fat diet (HFD)...

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Bibliographic Details
Main Authors: A. K. J. Gradel, T. Porsgaard, P. B. Brockhoff, T. Seested, J. Lykkesfeldt, H. H. F. Refsgaard
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Obesity Science & Practice
Subjects:
Online Access:https://doi.org/10.1002/osp4.326