Monocytes and Monocyte-Derived Antigen-Presenting Cells Have Distinct Gene Signatures in Experimental Model of Multiple Sclerosis

Monocytes and Monocyte-Derived Antigen-Presenting Cells Have Distinct Gene Signatures in Experimental Model of Multiple Sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease mediated by a complex interaction between the autoreactive lymphocytes and the effector myeloid cells within the central nervous system (CNS). In a murine model of MS, experimental autoimmune encephalomyelitis (EAE), Ly6Chi monocytes migrate...

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Bibliographic Details
Main Authors: Kelly L. Monaghan, Wen Zheng, Gangqing Hu, Edwin C. K. Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
experimental autoimmune encephalomyelitis
monocytes
antigen-presenting cells
RNA-Seq
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02779/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02779/full

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