Kuhuang injection exerts a protective effect by activating PPAR-γ in an in vitro model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineering

Context Kuhuang (KH) injection is a widely used anticholestatic drug in the clinic and the mechanisms are still unclear.Objective This study uses a new 3D tissue-engineered (TE) liver platform to study the ability of kuhuang to ameliorate liver injury induced by chlorpromazine (CPZ) and the possible...

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Bibliographic Details
Main Authors: Qiao Wu, Zhongping Duan, Long Huang, Zhijie Li
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2110128