RNase P Ribozyme Effectively Inhibits Human CC-Chemokine Receptor 5 Expression and Human Immunodeficiency Virus 1 Infection

Developing novel antiviral agents and approaches is essential for the treatment against human and zoonotic viruses. We had previously produced RNase P-based ribozyme variants capable of efficiently cleaving mRNA in vitro. Here, engineered ribozymes were constructed from an RNase P ribozyme variant t...

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Bibliographic Details
Main Authors: Bin Yan, Yujun Liu, Yuan-Chuan Chen, Isadora Zhang, Fenyong Liu
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Zoonotic Diseases
Subjects:
Online Access:https://www.mdpi.com/2813-0227/3/2/9