Protection from experimental cerebral malaria with a single intravenous or subcutaneous whole-parasite immunization

Abstract Cerebral malaria is a life-threatening complication of Plasmodia infection and a major cause of child mortality in Sub-Saharan Africa. We report that protection from experimental cerebral malaria in the rodent model is obtained by a single intravenous or subcutaneous whole-parasite immuniza...

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Bibliographic Details
Main Authors: Kirsten Heiss, Marion Irmgard Maier, Angelika Hoffmann, Roland Frank, Martin Bendszus, Ann-Kristin Mueller, Johannes Pfeil
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21551-2