Unbalanced occlusal loading elicited remodeling responses in growing rat temporomandibular joints and Notch1/Hes1 signaling pathway expression

Abstract Objective We aimed to assess the impact of unbalanced occlusal loading on the TMJ and the expression of the Notch1/Hes1 signaling pathway using a unilateral occlusal loss rat model. Methods We established a unilateral occlusal defect animal model. At three different times, all female Wistar...

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Bibliographic Details
Main Authors: Miao Xiao, Qi Yue, Zhenyao Qin, Xinyue Hang, Xin Chen, Shilei Ni
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-025-05631-0