IL-23 signaling is not an important driver of liver inflammation and fibrosis in murine non-alcoholic steatohepatitis models

Non-alcoholic fatty liver disease (NAFLD), represents an unmet medical need that can progress to non-alcoholic steatohepatitis (NASH), which, without intervention, can result in the development of cirrhosis and hepatocellular carcinoma (HCC). Inflammation is a pathological hallmark of NASH, and targ...

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Bibliographic Details
Main Authors: Jose E. Heredia, Clara Sorenson, Sean Flanagan, Victor Nunez, Charles Jones, Angela Martzall, Laurie Leong, Andres Paler Martinez, Alexis Scherl, Hans D. Brightbill, Nico Ghilardi, Ning Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477333/?tool=EBI