1α,25(OH)2D3(VD3) promotes Raddeanin A-induced anti-proliferative effects on HeLa cell apoptosis and autophagy through negative regulation of HPV18E6-E7/PD-L1/VDR axis

1α,25(OH)2D3(VD3) promotes Raddeanin A-induced anti-proliferative effects on HeLa cell apoptosis and autophagy through negative regulation of HPV18E6-E7/PD-L1/VDR axis

Raddeanin A (RA) has indicated suppressive effects on various human tumor cells, and insufficient vitamin D was associated with human papillomavirus (HPV) persistence and gynecological tumors. However, combined effects of RA and vitamin D on HPV-positive cells remain elusive. Herein, we aimed to inv...

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Bibliographic Details
Main Authors: Zhiyu Li, Biyun Xu, Yuexin Sun, Lanbo Zhou, Yue Tao, Wenjun Hou, Jun Bao, Jun Liu, Weixin Fan
Format: Article
Language:English
Published: Taylor & Francis Group 2022-01-01
Series:Bioengineered
Subjects:
vitamin d
raddeanin a (ra)
hela cells
apoptosis
autophagy
pd-l1
Online Access:http://dx.doi.org/10.1080/21655979.2021.2005223

Internet

http://dx.doi.org/10.1080/21655979.2021.2005223

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