Low host immune pressure may be associated with the development of hepatocellular carcinoma: a longitudinal analysis of complete genomes of the HBV 1762T, 1764A mutant

Low host immune pressure may be associated with the development of hepatocellular carcinoma: a longitudinal analysis of complete genomes of the HBV 1762T, 1764A mutant

BackgroundIt has been reported that hepatitis B virus (HBV) double mutations (A1762T, G1764A) are an aetiological factor of hepatocellular carcinoma (HCC). However, it is unclear who is prone to develop HCC, among those infected with the mutant. Exploring HBV quasispecies, which are strongly influen...

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Bibliographic Details
Main Authors: Zhi-Hua Jiang, Qin-Yan Chen, Hui-Hua Jia, Xue-Yan Wang, Lu-Juan Zhang, Xiao-Qian Huang, Tim J. Harrison, J. Brooks Jackson, Li Wu, Zhong-Liao Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
hepatitis B virus
hepatocellular carcinoma
mutations
next-generation sequencing
quasispecies
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1214423/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1214423/full

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