Glucocorticoid-Induced Leucine Zipper Alleviates Lung Inflammation and Enhances Bacterial Clearance during Pneumococcal Pneumonia

Glucocorticoid-Induced Leucine Zipper Alleviates Lung Inflammation and Enhances Bacterial Clearance during Pneumococcal Pneumonia

Pneumonia is a leading cause of morbidity and mortality. While inflammation is a host protective response that ensures bacterial clearance, a finely regulated response is necessary to prevent bystander tissue damage. Glucocorticoid (GC)-induced leucine zipper (GILZ) is a GC-induced protein with anti...

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Bibliographic Details
Main Authors: Jéssica Amanda Marques Souza, Antônio Felipe S. Carvalho, Lais C. Grossi, Isabella Zaidan, Leonardo Camilo de Oliveira, Juliana P. Vago, Camila Cardoso, Marina G. Machado, Geovanna V. Santos Souza, Celso Martins Queiroz-Junior, Eric F. Morand, Stefano Bruscoli, Carlo Riccardi, Mauro M. Teixeira, Luciana P. Tavares, Lirlândia P. Sousa
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
inflammation resolution
proresolving mediators
<i>Streptococcus pneumoniae</i>
acute lung injury
Online Access:https://www.mdpi.com/2073-4409/11/3/532

Internet

https://www.mdpi.com/2073-4409/11/3/532

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